PREVALENCE AND RISK FACTORS FOR HEPATITIS B INFECTION AMONG PREGNANT WOMEN ATTENDING ANTENATAL CLINICS IN GARISSA DISTRICT

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dc.contributor.author Mohammed, Ahmed Abade
dc.date.accessioned 2016-02-22T12:23:23Z
dc.date.available 2016-02-22T12:23:23Z
dc.date.issued 2016-02-22
dc.identifier.uri http://hdl.handle.net/123456789/1929
dc.description A thesis submitted in partial fulfillment for the Degree of Master of Science in Laboratory Management and Epidemiology in the Jomo Kenyatta University of Agriculture and Technology 2008 en_US
dc.description.abstract Hepatitis is a general term meaning inflammation of the liver, caused by a variety of different viruses such as Hepatitis A, B, C, D, and E. More than 2 billion people alive today have been infected with HBV at some time in their lives with 350 million of them remaining infected chronically and being carriers of the virus. A cross sectional study was carried out to determine the prevalence and risk factors for Hepatitis B infection among pregnant women attending ANC clinics in Garissa district. The study subjects were selected by systematic random sampling and every fourth client was included in the study after which a blood sample was removed for routine antennal profile. Left over blood samples were subjected to Hepatitis B screening by ELISA method after getting consent from the study subjects. Of the 384 pregnant women included in the study, 54 (14.1%) were sero-positive for Hepatitis B surface antigen. The significant risk factor for hepatitis positivity were female genital mutilation (COR-3.125; CI-95% 1.089-8.96; p=0.0262), blood transfusion history (COR-3.54, CI-95%-1.01-7.79 p=0.000135) and dental procedure history (COR-1.986; 95%CI- 1.11-3.54; p-0.0187). There was no significance difference with respect to presence of tattoo (p= 0.527), positive history of jaundice (p= 0.432), and history of surgical procedure (p= 0.538). Prevalence rate (14.1%) was found to be very high hence putting Garissa within the areas of high endemicity according to WHO criteria. Blood transfusion, history dental procedure and female genital mutilation were found to be associated with hepatitis B infection. Integration of monovalent hepatitis B vaccine into the national immunization and screening of antenatal mother for hepatitis B infection are some of the intervention strategies that need to be adopted in order to reduce the rate of hepatitis B infection. en_US
dc.description.sponsorship Dr Joseph Oundo CDC, Kenya Dr Kariuki Njenga CDC, Kenya Dr Jane Ngaira JKUAT, Kenya en_US
dc.language.iso en en_US
dc.publisher Laboratory Management and Epidemiology ,JKUAT en_US
dc.relation.ispartofseries MscLaboratory Management and Epidemiology;2008
dc.subject Laboratory Management and Epidemiology en_US
dc.title PREVALENCE AND RISK FACTORS FOR HEPATITIS B INFECTION AMONG PREGNANT WOMEN ATTENDING ANTENATAL CLINICS IN GARISSA DISTRICT en_US
dc.type Thesis en_US


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  • College of Health Sciences (COHES) [771]
    Medical Laboratory; Agriculture & environmental Biotecthology; Biochemistry; Molecular Medicine, Applied Epidemiology; Medicinal PhytochemistryPublic Health;

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