Abstract:
The inhibitory activities of aqueous and solvent extracts of twelve selected medicinal
plants were evaluated against biosynthesis of aflatoxin B1
(AFB1
) by Aspergillus flavus.
The A. flavus was isolated from maize, and aflatoxin B1
biosynthesis was confirmed by
comparison with standard AFB1
using TLC method. In vivo antiaflatoxigenic efficacies of
activity guided solvent extracts were determined in maize model system. All the extracts
showed varying degree of antifungal and AFB1
inhibitory activities, but chloroformic
extract of Albizia amara, Cassia spectabilis and Solanum indicum, and methanolic extract
of Acacia catechu, Albizia saman and Anogeissus latifolia showed the highest activity.
Further investigations on identification of active principles from these plants are needed
to develop plant based formulations for management of A. flavus growth and AFB1
contamination in food grains.
Keywords: Antiaflatoxigenic, Maize, Plant extract
