dc.contributor.author |
Nyamogoba, H DN |
|
dc.contributor.author |
Kikuvi, G |
|
dc.contributor.author |
Mbuthia, G |
|
dc.contributor.author |
Mining, S |
|
dc.contributor.author |
Biegon, R |
|
dc.contributor.author |
Mpoke, S |
|
dc.contributor.author |
Menya, D |
|
dc.contributor.author |
Waiyaki, P G |
|
dc.date.accessioned |
2017-05-24T08:42:09Z |
|
dc.date.available |
2017-05-24T08:42:09Z |
|
dc.date.issued |
2017-05-24 |
|
dc.identifier.uri |
https://www.ajol.info/index.php/ahs/article/view/84445 |
|
dc.identifier.uri |
http://hdl.handle.net/123456789/3164 |
|
dc.description.abstract |
Background: Tuberculosis (TB) and HIV co-infections have a global prevalence with devastating morbidity and massive mortality, Sub-Saharan Africa being the worst hit.
Objectives: To evaluate the prevalence of TB-HIV co-infection and demonstrate the confusion caused by NTM and HIV/AIDS co-infection in TB diagnosis and treatment in western Kenya.
Methods: In a cross-sectional study carried out at 10 hospitals in western Kenya, sputa from consenting 872 TB suspects underwent microscopy, and culture on Lowenstein-Jensen and Mycobacteria Growth Index Tube media. Isolates were identified using the Hain’s GenoType® Mycobacterium CM and GenoType® Mycobacterium AS kits. A total of 695 participants were screened for HIV using Uni-GoldTM test and positives confirmed with the enzyme linked immunosorbent assay.
Results: A total of 346 (39.7%) participants were diagnosed with TB. Out of the 346 TB cases, 263 (76%) were tested for HIV infection and 110 (41.8%) of these were sero-positive (co-infected). The female to male TB-HIV co-infection prevalence ratio (PR) was 1.35. This study reports isolation of non-tuberculous mycobacteria from TB suspects at a rate of 1.7%.
Conclusion: A high TB-HIV co-infection rate was observed in this study. The NTM disease could be misdiagnosed and treated as TB in western Kenya. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
African Health Sciences |
en_US |
dc.relation.ispartofseries |
African Health Sciences;2012; 12(3):305 - 311 |
|
dc.subject |
Tuberculosis |
en_US |
dc.subject |
HIV co-infection |
en_US |
dc.subject |
high prevalence |
en_US |
dc.subject |
TB diagnosis |
en_US |
dc.subject |
Kenya |
en_US |
dc.subject |
JKUAT |
en_US |
dc.title |
HIV co-infection with tuberculous and non-tuberculous mycobacteria in western Kenya: challenges in the diagnosis and management |
en_US |
dc.type |
Article |
en_US |