Abstract:
Endometriosis is a benign, estrogen-dependent disease and is now recognized as an
enigmatic disease owing to its various clinical manifestations and locations. The lack of
a reliable and specific method for the early detection of endometriosis often results in
delayed diagnosis. So far, research has born inadequate findings regarding understanding
the basic etiology or pathophysiology of endometriosis. Animal models that accurately
represent the cellular and molecular changes associated with the initiation and progression
of human endometriosis have significant potential to facilitate the development of
better methods for the early detection and treatment of endometriosis. A number of
animal model systems have been developed for the study of this disease. These models
replicate many of the known salient features of human endometriosis. This review
provides an insight into the use of the baboon model for studies focused on understanding
human endometriosis