Potential involvement of the immune system in the development of endometriosis

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dc.contributor.author Kyama, Cleophas M
dc.contributor.author Debrock, Sophie
dc.contributor.author Mwenda, Jason M
dc.contributor.author D'Hooghe, Thomas M
dc.date.accessioned 2017-02-06T13:23:14Z
dc.date.available 2017-02-06T13:23:14Z
dc.date.issued 2017-02-06
dc.identifier.uri http://www.rbej.com/content/1/1/123
dc.identifier.uri http://hdl.handle.net/123456789/2600
dc.description.abstract This article presents an overview of immunological factors and their role in the development of endometriosis, with emphasis on inflammatory cytokines, growth and adhesion factors. Although retrograde menstruation is a common phenomenon among women of reproductive age, not all women who have retrograde menstruation develop endometriosis. The development of endometriosis is hypothesised to be a complex process, which may be facilitated by several factors, including the quantity and quality of endometrial cells in peritoneal fluid (PF), increased inflammatory activity in PF, increased endometrial-peritoneal adhesion and angiogenesis, reduced immune surv