Browsing Research Articles by Subject "human African trypanosomiasis (HAT)"

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CHANGES IN SOME URINE PARAMETERS IN VERVET MONKEY MODEL OF TRYPANOSOMIASIS: TOWARDS NON‐INVASIVE DIAGNOSIS OF SLEEPING SICKNESS

Waita, I. M.; . Karanja, S. M; A. G., Kiarie; N. W., Maina (2017-03-21)

The current diagnostic procedures for human African trypanosomiasis (HAT) are invasive. Urine being a non‐invasive sample could be an alternative to the current screening that is based on blood sampling and cerebrospinal ...
Development of a safer laboratory vervet monkey model for the study of human African trypanosomiasis

Waema, Maxwell; Maina, Naomi; Karanja, Simon; Gachie, Beatrice; Ngotho, Maina; Kagira, John (ajlmonline org, 2017-02-09)

Background: There are three subspecies of Trypanosoma brucei: T. b. gambiense, T. b. rhodesiense and T. b. brucei. The first two are infectious to humans, whilst T. b. brucei is not. Identifying an animal model of T. b. ...
Loop Mediated Isothermal Amplification for Detection of Trypanosoma brucei gambiense in Urine and Saliva Samples in Nonhuman Primate Model

Ngotho, Maina; Kagira, JohnMaina; Gachie, Beatrice Muthon; Karanja, Simon Muturi; Waema, Maxwell Wambua; Maranga, Dawn Nyawira; Maina, Naomi Wangari (Hindawi Publishing Corporation, 2017-02-09)

Human African trypanosomiasis (HAT) is a vector-borne parasitic zoonotic disease. The disease caused by Trypanosoma brucei gambiense is themost prevalent in Africa. Early diagnosis is hampered by lack of sensitive diagnostic ...
Pharmacology of DB844, an Orally Active aza Analogue of Pafuramidine, in a Monkey Model of Second Stage Human African Trypanosomiasis

Thuita, John K.; Kagira, John M.; Denton, Cathrine L.....Et al (PLOS, 2017-02-09)

Novel drugs to treat human African trypanosomiasis (HAT) are still urgently needed despite the recent addition of nifurtimox-eflornithine combination therapy (NECT) to WHO Model Lists of Essential Medicines against second ...
Prevalence and Types of Coinfections in Sleeping Sickness Patients in Kenya (2000/2009)

Kagira, J.M.; Maina, N; Njenga, J.; Karanja, S. M.; Karori, S. M.; Ngotho, J.M. (Hindawi Publishing Corporation, 2017-02-27)

The occurrence of coinfections in human African trypanosomiasis (HAT) patients was investigated using a retrospective data of hospital records at the National Sleeping Sickness Referral Hospital in Alupe, Kenya. A total ...

Browsing Research Articles by Subject "human African trypanosomiasis (HAT)"

Browsing Research Articles by Subject "human African trypanosomiasis (HAT)"

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