Browsing by Author "Ngotho, Maina"

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Detection of Natural Toxoplasma gondii Infection in Chicken in Thika Region of Kenya Using Nested Polymerase Chain Reaction

Mose, John Mokua; Kagira, JohnMaina; Karanja, SimonMuturi; Ngotho, Maina; Kamau, David Muchina; Njuguna, Adele Nyambura; Maina, Naomi Wangari (Hindawi Publishing Corporation, 2017-02-09)

Thedetection of Toxoplasma gondii in free-range chickens is a good indicator of possible risk to human beings.Theaimof this study was to investigate the occurrence of T. gondii in free-range chicken using polymerase chain ...
Development of a safer laboratory vervet monkey model for the study of human African trypanosomiasis

Waema, Maxwell; Maina, Naomi; Karanja, Simon; Gachie, Beatrice; Ngotho, Maina; Kagira, John (ajlmonline org, 2017-02-09)

Background: There are three subspecies of Trypanosoma brucei: T. b. gambiense, T. b. rhodesiense and T. b. brucei. The first two are infectious to humans, whilst T. b. brucei is not. Identifying an animal model of T. b. ...
Haematology of experimental Trypanosoma brucei rhodesiense infection in vervet monkeys

Kagira, John M; Thuita, John K; Ngotho, Maina; Mdachi, Raymond; Mwangangi, David M; Ndung’u, Joseph M (2017-02-09)

Haematological aberrations associated with human infective trypanosomes were investigated in the vervet monkey model of the Rhodesian sleeping sickness. Four monkeys were infected intravenously with 104 Trypanosoma brucei ...
IgM and IL-10 up regulation is related to parasite numbers and relapse parasitaemia during late stage disease in vervet monkeys infected with Trypanosoma b. rhodesiense

Ngotho, Maina; Kagira, John; Jensen, Henrik; Karanja, Simon; Farah, Idle; Hau, Jann (BioMed Central, 2017-02-09)

Human African trypanosomiasis is an infectious, neglected, vector-borne protozoan disease which has an early haemolymphatic phase followed by meningoencephalitis due to neuroinvasion of the central nervous system by ...
Loop Mediated Isothermal Amplification for Detection of Trypanosoma brucei gambiense in Urine and Saliva Samples in Nonhuman Primate Model

Ngotho, Maina; Kagira, John Maina; Gachie, Beatrice Muthoni; Karanja, Simon Muturi; Waema, Wambua Waema; Maranga, Dawn Nyawira; Maina, Naomi Wangari (JKUAT, 2016-09-21)

Human African trypanosomiasis (HAT) is a vector-borne parasitic zoonotic disease. The disease caused by Trypanosoma brucei gambiense is themost prevalent in Africa. Early diagnosis is hampered by lack of sensitive diagnostic ...
Loop Mediated Isothermal Amplification for Detection of Trypanosoma brucei gambiense in Urine and Saliva Samples in Nonhuman Primate Model

Ngotho, Maina; Kagira, JohnMaina; Gachie, Beatrice Muthon; Karanja, Simon Muturi; Waema, Maxwell Wambua; Maranga, Dawn Nyawira; Maina, Naomi Wangari (Hindawi Publishing Corporation, 2017-02-09)

Human African trypanosomiasis (HAT) is a vector-borne parasitic zoonotic disease. The disease caused by Trypanosoma brucei gambiense is themost prevalent in Africa. Early diagnosis is hampered by lack of sensitive diagnostic ...
Loop Mediated Isothermal Amplification for Detection of Trypanosoma brucei gambiense in Urine and Saliva Samples in Nonhuman Primate Model

Ngotho, Maina; Kagira, JohnMaina; Gachie, Beatrice Muthoni (2017-02-27)

Human African trypanosomiasis (HAT) is a vector-borne parasitic zoonotic disease. The disease caused by Trypanosoma brucei gambiense is themost prevalent in Africa. Early diagnosis is hampered by lack of sensitive diagnostic ...
Pathogenicity of bloodstream and cerebrospinal fluid forms of Trypanosoma brucei rhodesiense in Swiss White Mice

Ndung’u, Kariuki; Ngotho, Maina; Kinyua, Johnson; Kagira, John; Guya, Samuel; Ndung’u, Joseph; Murilla, Grace (2017-02-09)

Trypanosoma brucei rhodesiense (T.b.r.), the causative agent of the East African form of human African trypanosomiasis (HAT), is capable of crossing the blood brain barrier and invade the central nervous system (CNS). ...
Questionnaire Survey on the Occurrence of Risk factors for Toxoplasma gondii infection amongst Farmers in Thika District, Kenya

Kagira, John; Ngotho, Maina; Mbugua, Gabriel; Karanja, Simon (2017-02-28)

A survey was conducted to determine the occurrence of risk factors for Toxoplasma gondii infection amongst farmers in Thika District, Kenya. Interviews were conducted in a total of 385 households using a structured ...
Socioeconomic and health implications of human–wildlife interactions in Nthongoni, Eastern Kenya

Mwangi, Danson K.; Akinyi, Mercy; Maloba, Fredrick; Ngotho, Maina; Kagira, John; Ndeereh, David; Kivai, Stanislaus (BioOne, 2017-02-10)

The human population in Kenya has doubled over the last 25 years and is expected to rise twofold by 2050.Thus,pressure for human space has led to encroachment into wildlife habitats, increasing human–wildlife interactions. ...
Virulence and pathogenicity of three Trypanosoma brucei rhodesiense stabilates in a Swiss white mouse model

Kariuki, Christopher; Kagira, John M.; Mwadime, Victor; Ngotho, Maina (ajlmonline org, 2017-02-09)

Background: A key objective in basic research on human African trypanosomiasis (HAT) is developing a cheap and reliable experimental model of the disease for use in pathogenesis and drug studies. Objective: With a view ...

Browsing by Author "Ngotho, Maina"

Browsing by Author "Ngotho, Maina"

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