Browsing by Author "Kagira, John M."

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Pharmacology of DB844, an Orally Active aza Analogue of Pafuramidine, in a Monkey Model of Second Stage Human African Trypanosomiasis

Thuita, John K.; Kagira, John M.; Denton, Cathrine L.....Et al (PLOS, 2017-02-09)

Novel drugs to treat human African trypanosomiasis (HAT) are still urgently needed despite the recent addition of nifurtimox-eflornithine combination therapy (NECT) to WHO Model Lists of Essential Medicines against second ...
Prevalence of endoparasites in cattle within urban and peri-urban areas of Lake Victoria Basin, Kenya with special reference to zoonotic potential

Kanyari1, Paul W.N.; Kagira, John M.; Mhoma, Jumanne R.L (2017-02-09)

The growing human population and the tendency to keep livestock in urban settlements in developing countries in particular has caused concern due to the unplanned nature of such developments and the constraints they ...
Trypanosoma brucei rhodesiense Transmitted by a Single Tsetse Fly Bite in Vervet Monkeys as a Model of Human African Trypanosomiasis

Thuita, John K.; Kagira, John M.; David, Mwangangi; Matovu, Enock; Turner, C. M. R.; Masiga, Daniel (plosntds, 2017-02-08)

We have investigated the pathogenicity of tsetse (Glossina pallidipes)-transmitted cloned strains of Trypanosoma brucei rhodesiense in vervet monkeys. Tsetse flies were confirmed to have mature trypanosome infections by ...
Virulence and pathogenicity of three Trypanosoma brucei rhodesiense stabilates in a Swiss white mouse model

Kariuki, Christopher; Kagira, John M.; Mwadime, Victor; Ngotho, Maina (ajlmonline org, 2017-02-09)

Background: A key objective in basic research on human African trypanosomiasis (HAT) is developing a cheap and reliable experimental model of the disease for use in pathogenesis and drug studies. Objective: With a view ...

Browsing by Author "Kagira, John M."

Browsing by Author "Kagira, John M."

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